Gene description for PDCD6IP
Gene name programmed cell death 6 interacting protein
Gene symbol PDCD6IP
Other names/aliases -
Species Bos taurus
 Experiment description of studies that identified PDCD6IP in Bovine milk

1
Experiment ID1048
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 28725021   
OrganismBos taurus
Experiment descriptionBovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
AuthorsSamuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S.
Journal name Sci Rep.
Publication year2017
SampleBovine milk
Sample nameBovine milk - mature milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.08.1.24 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
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2
Experiment ID1045
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
Western blotting
PubMed ID 28725021   
OrganismBos taurus
Experiment descriptionBovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
AuthorsSamuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S.
Journal name Sci Rep.
Publication year2017
SampleBovine milk
Sample nameBovine milk - colostrum 12 h and 24 h
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.08.1.24 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

3
Experiment ID1046
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
Western blotting
PubMed ID 28725021   
OrganismBos taurus
Experiment descriptionBovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
AuthorsSamuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S.
Journal name Sci Rep.
Publication year2017
SampleBovine milk
Sample nameBovine milk - colostrum 72 h
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.08.1.24 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

4
Experiment ID1047
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
Western blotting
PubMed ID 28725021   
OrganismBos taurus
Experiment descriptionBovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
AuthorsSamuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S.
Journal name Sci Rep.
Publication year2017
SampleBovine milk
Sample nameBovine milk - colostrum 48 h
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density1.08.1.24 g/mL
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

5
Experiment ID1163
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29904572   
OrganismBos taurus
Experiment descriptionA subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.
AuthorsBenmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P.
Journal name J Extracell Vesicles
Publication year2017
SampleBovine milk
Sample namePellet, 12000 g
Isolation/purification methodsDifferential centrifugation
Density gradient centrifugation
Flotation density1.11-1.14 g/mL
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

6
Experiment ID1164
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29904572   
OrganismBos taurus
Experiment descriptionA subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.
AuthorsBenmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P.
Journal name J Extracell Vesicles
Publication year2017
SampleBovine milk
Sample namePellet, 35000 g
Isolation/purification methodsDifferential centrifugation
Density gradient centrifugation
Flotation density1.11-1.14 g/mL
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

7
Experiment ID1165
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29904572   
OrganismBos taurus
Experiment descriptionA subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.
AuthorsBenmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P.
Journal name J Extracell Vesicles
Publication year2017
SampleBovine milk
Sample namePellet, 70000 g
Isolation/purification methodsDifferential centrifugation
Density gradient centrifugation
Flotation density1.11-1.14 g/mL
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

8
Experiment ID1166
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 29904572   
OrganismBos taurus
Experiment descriptionA subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.
AuthorsBenmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P.
Journal name J Extracell Vesicles
Publication year2017
SampleBovine milk
Sample namePellet, 100000 g
Isolation/purification methodsDifferential centrifugation
Density gradient centrifugation
Flotation density1.11-1.14 g/mL
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

9
Experiment ID2211
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 37043568   
OrganismBos taurus
Experiment descriptionMilk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis
AuthorsTong L, Zhang S, Liu Q, Huang C, Hao H, Tan MS, Yu X, Lou CKL, Huang R, Zhang Z, Liu T, Gong P, Ng CH, Muthiah M, Pastorin G, Wacker MG, Chen X, Storm G, Lee CN, Zhang L, Yi H, Wang JW.
Journal name Sci Adv
Publication year2023
SampleBovine milk
Sample nameColostrum
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Centrifugal ultrafiltration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID2215
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35953855   
OrganismBos taurus
Experiment descriptionMilk-derived small extracellular vesicles: nanomaterials to promote bone formation
AuthorsDong M, Shi C, Yu X, Yang Q, Wu S, Liu R, Liu T, Wang L, Niu W.
Journal name J Nanobiotechnology
Publication year2022
SampleBovine milk
Sample nameMilk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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